So I'm trying Mint 18 as an alternative to Ubuntu for one of my machines. Drivers, etc are all installed and Boinc will run my Radeon cards fine if I start up the boinc-client manually, however if I reboot, Boinc (loaded automatically at startup) does not recognize them. It seems like Boinc might be just starting before the drivers or opencl libraries, etc are loaded?

I found this thread on the subject over at gpugrid: https://www.gpugrid.net/forum_thread.php?id=3533#33781

They describe a couple of different methods of trying to delay Boinc startup, but I have tried both and it hasn't fixed the issue. Are there any other ways to do this, or other thoughts on what could be wrong? I want the machine to be able to run itself if it restarts spontaneously for some reason.

I also found this thread here, describing the same issue: https://boinc.berkeley.edu/dev/forum_thread.php?id=6307

But the same possible fixes are mentioned, which seem to have no effect in later versions of linux?

I had the same issues with Mint and a 280x. I just learned to restart the client after it booted. I'm no Linux expert and never found a way to delay the BOINC startup either.